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Holocarboxylase synthetase deficiency natural cures

Holocarboxylase synthetase deficiency Definition

 Holocarboxylase synthetase deficiency is an inherited disorder in which the body is unable to utilize the vitamin biotin effectively. This disorder is classified as a multiple carboxylase deficiency, a group of disorders marked by impaired activity of certain enzymes that depend on biotin.

Holocarboxylase synthetase deficiency Diagnosis

 Initial studies should include the following: serum electrolyte levels; blood ammonia levels; urinalysis; and culture samples appropraite for an evaluation for sepsis.

Holocarboxylase synthetase deficiency Treatment

 Because of the acute and fulminant initial presentation, treatment is almost always started in the hospital. Once treatment has begun and the acute signs and symptoms have gone away, the child may be safely discharged and observed on an outpatient basis.

Holocarboxylase synthetase deficiency Symptoms and Signs

 The signs and symptoms of holocarboxylase synthetase deficiency generally appear within the first few months of life, but the age of onset varies. Affected infants often have a hard time feeding, breathing problems, a skin rash, hair loss (alopecia), and a lack of energy (lethargy). Immediate treatment and lifelong management with biotin supplements may prevent several of these complications. If left untreated, the disorder can result to delayed development, seizures, and coma. These medical problems may be life-threatening in a few cases.
Holocarboxylase synthetase deficiency Causes
 The gene locus has been mapped to band 21q22.1, with a limited number of allelic variants recognized.

Holocarboxylase synthetase deficiency by state

Holocarboxylase synthetase deficiency in Alabama
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Holocarboxylase synthetase deficiency in Armed Forces
Holocarboxylase synthetase deficiency in California
Holocarboxylase synthetase deficiency in Colorado
Holocarboxylase synthetase deficiency in Connecticut
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Holocarboxylase synthetase deficiency in District of Columbia
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Holocarboxylase synthetase deficiency in Pennsylvania
Holocarboxylase synthetase deficiency in Puerto Rico
Holocarboxylase synthetase deficiency in Rhode Island
Holocarboxylase synthetase deficiency in South Carolina
Holocarboxylase synthetase deficiency in South Dakota
Holocarboxylase synthetase deficiency in Tennessee
Holocarboxylase synthetase deficiency in Texas
Holocarboxylase synthetase deficiency in Utah
Holocarboxylase synthetase deficiency in Vermont
Holocarboxylase synthetase deficiency in Virginia
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Holocarboxylase synthetase deficiency in West Virginia
Holocarboxylase synthetase deficiency in Wisconsin
Holocarboxylase synthetase deficiency in Wyoming
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