Factor XIII Deficiency, Congenital natural cures |
Factor XIII Deficiency, Congenital Definition
Factor XIII Deficiency, Congenital -is a very uncommon hereditary blood disorder that is characterized by anomalous blood clotting resulting in abnormal bleeding. Factor XIII is fundamentally a 'plasma transglutaminase', which catalyzes the last step of coagulation cascade; it cross-links 'loose fibrin polymer' into an extremely organized structure. Defect in Factor XIII results to the symptoms of the deficiency.
Factor XIII Deficiency, Congenital Diagnosis
If Factor XIII deficiency is suspected, blood tests are performed. Other basis for diagnosis includes screening tests, functional assays, immunologic assays, and genotyping.
Factor XIII Deficiency, Congenital Treatment
Treatments include the supplementation of fresh frozen plasma or cryoprecipitate. Factor XIII concentrate has also been used to replace FXIII and treating bleeding. Prophylaxis is the choice for treatment strategy because FXIII levels that are above three to five percent are typically sufficient to stop spontaneous bleeding. Prophylactic therapy provides sufficient plasma levels in the majority of patients.
Factor XIII Deficiency, Congenital Symptoms and Signs
Manifestations of the deficiency include joint bleeding, brain bleeding, spontaneous abortions, menorrhagia, male infertility, too much bleeding around the umbilical cord, excessive bleeding after surgery or trauma, bleeding in soft tissue, poor healing of wound, and other bleeding problems.
Factor XIII Deficiency, Congenital Causes
The deficiency is typically caused by mutations in Catalytic A subunit. There are more than forty various mutations identified, resulting to extreme bleeding diathesis. Other diseases, such as Henoch-Schonlein Purpura and Sickle Cell Disease, can also cause the deficiency.
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Factor XIII Deficiency, Congenital by state |
Factor XIII Deficiency, Congenital in Alabama
Factor XIII Deficiency, Congenital in Alaska
Factor XIII Deficiency, Congenital in Arizona
Factor XIII Deficiency, Congenital in Arkansas
Factor XIII Deficiency, Congenital in Armed Forces
Factor XIII Deficiency, Congenital in California
Factor XIII Deficiency, Congenital in Colorado
Factor XIII Deficiency, Congenital in Connecticut
Factor XIII Deficiency, Congenital in Delaware
Factor XIII Deficiency, Congenital in District of Columbia
Factor XIII Deficiency, Congenital in Florida
Factor XIII Deficiency, Congenital in Georgia
Factor XIII Deficiency, Congenital in Hawaii
Factor XIII Deficiency, Congenital in Idaho
Factor XIII Deficiency, Congenital in Illinois
Factor XIII Deficiency, Congenital in Indiana
Factor XIII Deficiency, Congenital in Iowa
Factor XIII Deficiency, Congenital in Kansas
Factor XIII Deficiency, Congenital in Kentucky
Factor XIII Deficiency, Congenital in Louisiana
Factor XIII Deficiency, Congenital in Maine
Factor XIII Deficiency, Congenital in Maryland
Factor XIII Deficiency, Congenital in Massachusetts
Factor XIII Deficiency, Congenital in Michigan
Factor XIII Deficiency, Congenital in Minnesota
Factor XIII Deficiency, Congenital in Mississippi
Factor XIII Deficiency, Congenital in Missouri
Factor XIII Deficiency, Congenital in Montana
Factor XIII Deficiency, Congenital in Nebraska
Factor XIII Deficiency, Congenital in Nevada
Factor XIII Deficiency, Congenital in New Hampshire
Factor XIII Deficiency, Congenital in New Jersey
Factor XIII Deficiency, Congenital in New Mexico
Factor XIII Deficiency, Congenital in New York
Factor XIII Deficiency, Congenital in North Carolina
Factor XIII Deficiency, Congenital in North Dakota
Factor XIII Deficiency, Congenital in Ohio
Factor XIII Deficiency, Congenital in Oklahoma
Factor XIII Deficiency, Congenital in Oregon
Factor XIII Deficiency, Congenital in Pennsylvania
Factor XIII Deficiency, Congenital in Puerto Rico
Factor XIII Deficiency, Congenital in Rhode Island
Factor XIII Deficiency, Congenital in South Carolina
Factor XIII Deficiency, Congenital in South Dakota
Factor XIII Deficiency, Congenital in Tennessee
Factor XIII Deficiency, Congenital in Texas
Factor XIII Deficiency, Congenital in Utah
Factor XIII Deficiency, Congenital in Vermont
Factor XIII Deficiency, Congenital in Virginia
Factor XIII Deficiency, Congenital in Washington
Factor XIII Deficiency, Congenital in West Virginia
Factor XIII Deficiency, Congenital in Wisconsin
Factor XIII Deficiency, Congenital in Wyoming
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